
If you’ve been struggling with depression, anxiety, PTSD, or emotional pain that just won’t lift no matter what you try, you’re not alone. Many people reach a point where therapy and medication help only so much. You do the work, you show up, but that heavy feeling still lingers. At Samaria Behavioral Health Center in Tempe, we meet people every day who feel exactly that way — tired, frustrated, and looking for something that finally works.
One option that’s been changing the conversation around treatment-resistant depression is ketamine infusion therapy in Tempe, AZ. It’s not a magic fix, but for the right person, it can be a breakthrough.
What Ketamine Therapy Really Is
Ketamine has been used safely for decades as an anesthetic. Over the past several years, doctors discovered that in much smaller doses, it can help lift symptoms of depression, anxiety, and trauma much faster than traditional antidepressants.
Instead of working on serotonin like most antidepressants, ketamine acts on glutamate, a chemical that helps your brain cells communicate and form new connections. In simple terms, it “resets” parts of the brain that have gone quiet from years of depression. Some people describe it as helping them “feel again” after being emotionally numb for so long.
Most patients notice changes within hours or days, not weeks. That’s part of what makes it so powerful for people who’ve been stuck for too long.
What the Experience Is Like
A ketamine infusion takes place in a comfortable, quiet setting with a provider who stays with you through the entire process. You’ll be seated or reclined, connected to monitors for safety, and receive a slow IV infusion over about 40–60 minutes.
Many people describe the experience as dream-like or deeply relaxing. You may feel slightly detached from your body or surroundings — this is normal and passes quickly after the infusion ends. You’ll rest for a short time afterward, and you’ll need someone to drive you home.
Most people begin with a short series of treatments — typically six infusions spread over two or three weeks — followed by occasional booster sessions depending on how you respond.
How Medication Management Fits In

At Samaria, we don’t view ketamine as a replacement for everything else. It’s one piece of a larger plan. For some, ketamine jump-starts progress that stalled with medication or therapy. For others, it works best when combined with ongoing medication management or counseling.
Our providers spend time understanding your full history — what medications you’ve tried, what worked, what didn’t, and how you’ve been feeling day to day. If you’re taking antidepressants, we’ll talk about whether continuing them alongside ketamine makes sense. If you’ve had side effects or limited results from previous medications, we’ll look at safer or more effective options moving forward.
Medication management at Samaria means more than prescribing. It means listening, adjusting, and helping you find balance between treatment and daily life.
Who Might Benefit
Ketamine therapy may be a good fit if you’ve struggled with:
- Major depression that hasn’t responded to medication.
- Bipolar depression.
- Post-traumatic stress disorder (PTSD).
- Obsessive-compulsive disorder (OCD).
- Severe anxiety or panic attacks.
- Suicidal thoughts or hopelessness.
Before starting treatment, we’ll complete a full evaluation to make sure ketamine is safe and appropriate for you. Certain conditions — such as uncontrolled high blood pressure, specific heart problems, or a history of psychosis — may require a different approach.
Why People Choose Ketamine Infusion Therapy
People often come to us after years of trying everything else. What draws them to ketamine is hope — hope that something can finally shift. Many describe the treatment as giving them “a window” where they can think clearly, reconnect emotionally, or finally engage in therapy in a new way.
It’s not a cure, but it can be a reset. When combined with good support, lifestyle changes, and continued mental health care, that reset can last and grow stronger over time.
What Makes Samaria Behavioral Health Center Different
Our approach in Tempe is deeply personal. We don’t rush. We don’t use cookie-cutter treatment plans. Every person who walks through our door has a story — and our role is to listen to it.
Our team includes psychiatric providers experienced in mood disorders, trauma, addiction recovery, and integrative mental health. Whether you need ketamine therapy, medication management, or therapy alone, we tailor care around what you truly need, not what’s easiest to prescribe.
You’ll find a quiet, compassionate space to heal — whether that’s in our clinic or online — and a team that genuinely cares about your progress.
Taking the Next Step with Infusion Therapy in Tempe, AZ

If you’ve been wondering whether ketamine infusion therapy in Tempe, AZ, might finally help you feel better, start by scheduling a consultation. We’ll talk about your symptoms, your history, and your goals. Together, we’ll decide whether ketamine is the right step or if another path would be better.
Healing doesn’t happen overnight, but it does happen — and you don’t have to face it alone.
At Samaria Behavioral Health Center in Tempe, AZ, we’re here to help you find what works for you, not just what’s common. Real healing starts when you’re seen, heard, and understood.
Let’s begin that journey together.
Explore Healing with Ketamine Infusion Therapy in Tempe, AZ
Have you reached the point where traditional treatments don’t feel like enough? Wondering if there might be another path forward? You don’t have to keep searching alone. At Samaria Behavioral Health, we offer ketamine infusion therapy in Tempe, AZ, paired with medication management, to help you move toward relief in a supportive and professional setting.
This is not about quick fixes—it’s about giving your mind and body the chance to reset, rebuild, and heal in new ways.
Here’s how to get started working with our team:
- Call (480) 471-8980 to schedule a consultation and learn how ketamine infusion therapy may fit into your treatment plan.
- Email info@samariabehavioral.com to connect with our team and book your first session.
- Begin treatment with guidance from compassionate providers who are dedicated to your stability, clarity, and long-term healing.
You don’t have to keep carrying the weight of “what if nothing works.” With the right support, new possibilities for recovery are within reach.
Comprehensive Care for Mental Health in Tempe, AZ
At Samaria Behavioral Health Center, we understand that healing looks different for everyone. That’s why we provide innovative treatment options like ketamine infusion therapy in Tempe, AZ, offering hope for those who haven’t found relief through traditional methods. Delivered safely and with expert oversight, ketamine can help reduce symptoms of depression, anxiety, and other mental health concerns by working on both the brain and the emotions—restoring balance, clarity, and motivation.
In addition to ketamine therapy, we provide a wide range of mental health services that address the whole person. Our clinicians specialize in ADHD evaluations and ADHD treatment, therapy for depression, anxiety, and bipolar disorder, and supportive care for individuals managing alcohol or opioid use. For those in need of more structure, our Intensive Outpatient Program (IOP) combines flexibility with deeper levels of support—helping clients make meaningful progress while continuing with daily responsibilities.
We also integrate restorative and mind-body approaches, including IV hydration therapy, outpatient psychiatry, postpartum mental health support, and treatment for PMDD. Every service we provide is rooted in compassion and clinical expertise, because at Samaria Behavioral Health Center, we believe healing is most effective when it’s tailored to the individual.